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Microscopic Polyangiitis
Microscopic polyangiitis is a pauci-immune nongranulomatous necrotizing vasculitis that (1) affects small blood vessels (capillaries, venules, or arterioles), (2) often causes glomerulonephritis and pulmonary capillaritis,
Primary Angiitis of the Central Nervous System
Primary angiitis of the CNS is a syndrome with several possible causes that produces small- and medium-sized vasculitis limited to the brain and spinal cord.
Behçet Disease
Named after the Turkish dermatologist who first described it, Behçet disease is of unknown cause and most commonly occurs in persons of Asian, Turkish, or
Relapsing Polychondritis
This disease is characterized by inflammatory destructive lesions of cartilaginous structures, principally the ears, nose, trachea, and larynx. Nearly 40% of cases are associated with
IgA Vasculitis (Henoch-Schonlein Purpura)
IgA vasculitis (Henoch-Schönlein purpura), the most common systemic vasculitis in children, occurs in adults as well. Typical clinical features are palpable purpura, arthritis, and hematuria.
Cryoglobulinemia
Cryoglobulinemia can be associated with an immune-complex–mediated, small-vessel vasculitis. Chronic infection with hepatitis C is the most common underlying condition; cryoglobulinemic vasculitis also can occur
Levamisole-Associated Purpura
Exposure to levamisole, a prevalent adulterant of illicit cocaine in North America, can induce a distinctive clinical syndrome of retiform purpura and cutaneous necrosis affecting
Eosinophilic Granulomatosis with Polyangiitis
Eosinophilic granulomatosis with polyangiitis (previously called Churg-Strauss syndrome) is an ANCA-associated vasculitis (along with granulomatosis with polyangiitis and microscopic polyangiitis), although the presence of ANCA
Granulomatosis with Polyangiitis
Granulomatosis with polyangiitis (formerly Wegener granulomatosis), which has an estimated incidence of approximately 12 cases per million individuals per year, is one of three vasculitides
Tuberculous Arthritis
Infection of peripheral joints by M. tuberculosis usually presents as a monoarticular arthritis lasting for weeks to months (or longer), but less often, it can
Spinal Tuberculosis (Pott Disease)
In the developing world, children primarily bear the burden of musculoskeletal tuberculosis. In the United States, however, musculoskeletal infection is more often seen in adults
Viral Arthritis
Arthralgias occur frequently in the course of acute infections with many viruses, but frank arthritis is uncommon with the notable exceptions of acute parvovirus B19